Story by Keith Giffen, J. M. DeMatteis. Art by Dale Eaglesham, Various. Cover by Philip Tan.
Tensions rise when the Scooby gang takes refuge in a seemingly safe town. But a new threat unlike the monsters they've faced before reveals itself. The gang now faces being torn apart by two enemies: the monsters... and themselves. The gang is left with two options: save whoever they can or watch as the human race fades into extinction. Collects issues #19-24.